Recently I was using CT Summation iBlaze v3 and I went to run it on a Windows 7 machine and all my cases were grayed out in Open Case with all the icons also grayed out in Case Explorer. After some tinkering, I found out that it is a compatibility issue with CT Summation iBlaze v3 in Windows 7.
Simple Run in Windows XP SP2/3 mode and it will fix the issue. If you are unable to select this option via the shortcut, simply run the troubleshoot compatibility link from right clicking. This should fix the issue.